Oven BBQ Squirrel Bake at 350°F for 2 hours or until meat is extremely tender, turning meat occasionally. Remove squirrels from sauce and set aside until cool enough to handle. Pull meat from bones and shred coarsely, discarding bones. Return meat to sauce and reheat on stovetop until heated through. Serve in a sandwich or over hot cooked rice or noodles. Barbecue sauce may be prepared up to a few days in advance. Entire recipe may be made up to 2 days ahead and refrigerated. Reheat gently over medium-low heat before serving. Meat will become tough if reheated at high a heat.